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Buy Lopimune.
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Lopimune Structure
- 200 mg - Lopinavir;
- 50 mg - Ritonavir;
Lopimune Indications
Lopimune is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection.
The following points should be considered when initiating therapy with Lopimune :
- Genotypic or phenotypic testing and/or treatment history should guide the use of Lopimune.
- Once-daily administration of Lopimune is not recommended for therapy-experienced adult patients or any pediatric patients.
- The use of other active agents with Lopimune is associated with a greater likelihood of treatment response.
Lopimune Dosage
Lopimune tablets may be taken with or without food. The tablets should be swallowed whole and not chewed, broken, or crushed.
Adult Patients:
Therapy-Naive Patients:
Lopimune tablets 800/200 mg (given as four 200/50 mg tablets) once-daily taken with or without food.
Lopimune tablets 400/100 mg (given as two 200/50 mg tablets) twice-daily taken with or without food.
Therapy-Experienced Patients:
Once-daily administration of Lopimune is not recommended in therapy-experienced patients.
Lopimune tablets 400/100 mg (given as two 200/50 mg tablets) twice-daily taken with or without food.
Concomitant Therapy: Efavirenz, nevirapine, (fos)amprenavir or nelfinavir:
Lopimune tablets should not be administered as a once-daily regimen in combination with efavirenz, nevirapine, (fos)amprenavir or nelfinavir .
A dose increase is recommended for all patients who use Lopimune tablets. The recommended dose of Lopimune tablets is 500/125
mg (such as two 200/50 tablets and one 100/25 mg tablet) twice daily in combination with efavirenz, nevirapine, (fos)amprenavir
or nelfinavir.
Lopimune Contraindications
Lopimune is contraindicated:
- with potent CYP3A inducers where significantly reduced lopinavir plasma concentrations may be associated with the potential for loss of virologic response and possible resistance and cross-resistance.
- with drugs that are highly dependent on CYP3A for clearance and for which elevated plasma concentrations are associated with serious and/or life-threatening reactions.
- in patients with previously demonstrated clinically significant hypersensitivity to any of its ingredients, including ritonavir.
Lopimune Form
Container of 60 tablets.
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