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Risofos Tablets Structure
- 75 mg - Risedronate Sodium;
Risofos Indications
Risofos 75 is indicated for the treatment and prevention of osteoporosis in postmenopausal women.
Treatment of Osteoporosis
In postmenopausal women with osteoporosis, risedronate increases BMD and reduces the incidence of vertebral fractures and a composite endpoint of non-vertebral osteoporosis-related fractures.
Prevention of Osteoporosis
Risofos 75 may be considered in postmenopausal women who are at risk of developing osteoporosis and for whom the desired clinical
outcome is to maintain bone mass and to reduce the risk of fracture. Factors such as family history of osteoporosis,
previous fracture, smoking, BMD (at least 1 SD below the pre-menopausal mean), high bone turnover, thin body frame,
Caucasian or Asian race, and early menopause are associated with an increased risk of developing osteoporosis and fractures.
The presence of these risk factors may be important when considering the use of risedronate for prevention of osteoporosis.
Risofos Dosage
Risofos 75 should be taken at least 30 minutes before the first food or drink of the day other than water. To facilitate
delivery to the stomach, Risofos 75 should be swallowed while the patient is in an upright position and with a full glass of
plain water (6 to 8 oz). Patients should not lie down for 30 minutes after taking the medication. Patients should receive supplemental
calcium and vitamin D if dietary intake is inadequate. Calcium supplements and calcium-, aluminum-, and magnesium-containing medications may
interfere with the absorption of Risofos 75 and should be taken at a different time of the day. Risofos 75 is not
recommended for use in patients with severe renal impairment (creatinine clearance <30 mL/min). No dosage adjustment is
necessary in patients with a creatinine clearance >/=30 mL/min or in the elderly.
Treatment of Postmenopausal Osteoporosis
One 75 mg tablet orally, taken on two consecutive days for a total of two tablets each month.
Prevention of Postmenopausal Osteoporosis
One 75 mg tablet orally, taken on two consecutive days for a total of two tablets each month.
If both tablets are missed, take one Risofos 75 mg tablet in the morning after the day it is remembered and then the other tablet on the next consecutive morning.
If one or both tablets of Risofos 75 mg on two consecutive days/month are missed, and the next month`s scheduled doses are more than 7 days away, the patient should be instructed as follows:
If one or both tablets of Risofos 75 mg on two consecutive days/month are missed, and the next month`s scheduled doses are within 7 days, patients should wait until their next month`s scheduled doses and then continue taking Risofos 75 mg on two consecutive days/month as originally scheduled.
If only one Risofos 75 mg tablet is missed, take the missed tablet in the morning after the day it is remembered.
Patients should then return to taking their Risofos 75 mg on two consecutive days/ month as originally scheduled. Patients should not take more than two 75 mg tablets within 7 days.
Risofos Contraindications
- Known hypersensitivity to any component of this product;
- Inability to stand or sit upright for at least 30 minutes;
- Hypocalcaemia;
Risofos Form
Blister pack of 2 tablets.
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